Dr. Michelle Le Beau leads CPRIT’s Academic Research program in supporting innovative cancer research and recruiting world-class cancer researchers to Texas institutions. Her distinguished research career has focused on basic and translational research. She is recognized for her work identifying recurring chromosomal abnormalities and defining the clinical and genetic subsets of leukemia, characterizing the genetic pathways that lead to hematological malignancies, and the application of fluorescence in situ hybridization for clinical diagnostics and gene mapping.
Dr. Le Beau has also studied therapy-related neoplasms (t-MN), an aggressive myeloid leukemia developing after therapy for a primary malignancy. Dr. Le Beau and her colleagues are credited with recognizing several distinct cytogenetic and clinical subtypes of t-MN that are closely associated with the nature of the preceding treatment and are now recognized by the World Health Organization classification. Prior to joining CPRIT in October 2021, Dr. Le Beau was the Arthur and Marian Edelstein Professor of Medicine and Director of the University of Chicago Medicine Comprehensive Cancer Center, which she led for 17 years. A graduate of Purdue University, Dr. Le Beau earned her M.S. and Ph.D. in Pathology from the University of Illinois at the Medical Center.
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